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Tocris/CINPA 1/5605/10/10 mg
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Tocris/CINPA 1/5605/10/10 mg
品牌 / 
Tocris
货号 / 
5605/10
美元价:
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数    量:
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4000-520-616
Description:PotentCARantagoNIST
ChemicalName:Ethyl[5-[(diethylamino)acetyl]-10,11-dihydro-5H-dibenz[b,f]azepin-3-yl]carbamate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentCARantagonist(IC50=70nM).Exhibits>90-foldselectivityforCARoverpregnaneXreceptor(PXR).AlsoselectiveoverapanelofothernuclearreceptorsincludingFXR,LXR,PPARγandRXR.

CompoundLibraries

CINPA1isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt395.49
FormulaC23H29N3O3
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber102636-74-8
PubChemID969470
InChIKeyAYQBYSPEGRYKFA-UHFFFAOYSA-N
SmilesO=C(CN(CC)CC)N1C2=C(C=CC=C2)CCC3=C1C=C(NC(OCC)=O)C=C3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO39.55100
ethanol39.55100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight395.49.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.53mL12.64mL25.29mL
5mM0.51mL2.53mL5.06mL
10mM0.25mL1.26mL2.53mL
50mM0.05mL0.25mL0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet