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Description:FFA2agoNIST;alsoexhibitspositiveallostericmodulatoryactivity
ChemicalName:4-chloro-α-(1-methylethyl)-N-2-thiazolylbenzeneacetamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
FreefattyacidreceptorFFA2agonist(pEC50=6.38)andpositiveallostericmodulator.Bindsatasitedistinctfromtheorthostericsite;modulatestheactivityofshort-chainfattyacidsatFFA2viatheFFA2secondextracellularloop(ECL2).
CompoundLibraries
4-CMTBisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 294.8 |
Formula | C14H15ClN2OS |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 300851-67-6 |
PubChemID | 4307629 |
InChIKey | AZYDQCGCBQYFSE-UHFFFAOYSA-N |
Smiles | ClC1=CC=C(C(C(C)C)C(NC2=NC=CS2)=O)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 29.48 | 100 | |
ethanol | 5.9 | 20 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight294.8.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.39mL | 16.96mL | 33.92mL |
5mM | 0.68mL | 3.39mL | 6.78mL |
10mM | 0.34mL | 1.7mL | 3.39mL |
50mM | 0.07mL | 0.34mL | 0.68mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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