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Tocris/4-CMTB/4642/10/10 mg
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Tocris/4-CMTB/4642/10/10 mg
品牌 / 
Tocris
货号 / 
4642/10
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4000-520-616
Description:FFA2agoNIST;alsoexhibitspositiveallostericmodulatoryactivity
ChemicalName:4-chloro-α-(1-methylethyl)-N-2-thiazolylbenzeneacetamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

FreefattyacidreceptorFFA2agonist(pEC50=6.38)andpositiveallostericmodulator.Bindsatasitedistinctfromtheorthostericsite;modulatestheactivityofshort-chainfattyacidsatFFA2viatheFFA2secondextracellularloop(ECL2).

CompoundLibraries

4-CMTBisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt294.8
FormulaC14H15ClN2OS
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber300851-67-6
PubChemID4307629
InChIKeyAZYDQCGCBQYFSE-UHFFFAOYSA-N
SmilesClC1=CC=C(C(C(C)C)C(NC2=NC=CS2)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO29.48100
ethanol5.920

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight294.8.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.39mL16.96mL33.92mL
5mM0.68mL3.39mL6.78mL
10mM0.34mL1.7mL3.39mL
50mM0.07mL0.34mL0.68mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet