Tocris中国试剂购买网站品牌试剂实验Tocris Bioscience代理,Tocris/CS 2100/4543/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/CS 2100/4543/10/10 mg

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Tocris

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4543/10

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Description:SelectiveS1P₁agoNIST

ChemicalName:1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxADIazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylicacid

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Sphingosine-1-phosphatereceptor1(S1P₁)agonist(EC₅₀=4.0nM).Exhibits5000-foldselectivityforhumanS1P₁overS1P₃.Displaysefficacyinaratadjuvant-inducedarthritismodel.

TechnicalData

M.Wt	461.53
Formula	C₂₅H₂₃N₃O₄S
Storage	Storeat+4°C
Purity	≥97%(HPLC)
CASNumber	913827-99-3
PubChemID	11977938
InChIKey	DWVJASHDNJMDNH-UHFFFAOYSA-N
Smiles	CCC1=C(C2=NOC(C4=CC=C(OC5=CC=CC=C5)C=C4)=N2)SC(CN3CC(C(O)=O)C3)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	2.31	5mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight461.53.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.17mL	10.83mL	21.67mL
5mM	0.43mL	2.17mL	4.33mL
10mM	0.22mL	1.08mL	2.17mL
50mM	0.04mL	0.22mL	0.43mL

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