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Description:SelectiveandpotentμantagoNIST
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potentandselectiveμopioidreceptorantagonist(IC50=3.5nM).Displays>1200-foldselectivityoverδopioidandsomatostatinreceptors.Brainpenetrantandactiveinvivo.
TechnicalData
M.Wt | 1104.32 |
Formula | C51H69N13O11S2 |
Sequence | FCYWRTXT (Modifications:Phe-1=D-Phe,Trp-4=D-Trp,X=Pen,Disulfidebridgebetween2-7,Thr-8=C-terminalamide) |
Storage | Desiccateat-20°C |
CASNumber | 103429-32-9 |
PubChemID | 90479802 |
InChIKey | OFMQLVRLOGHAJI-KOFBULAQSA-N |
Smiles | [H]N[C@H](CC1=CC=CC=C1)C(=O)N[C@H]1CSSC(C)(C)C(NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=C(O)C=C2)NC1=O)[C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solubility | Solubleto1mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight1104.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 0.91mL | 4.53mL | 9.06mL |
5mM | 0.18mL | 0.91mL | 1.81mL |
10mM | 0.09mL | 0.45mL | 0.91mL |
50mM | 0.02mL | 0.09mL | 0.18mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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