Tocris报价单 TOCRIS 4372-10MG,Tocris/CU CPT 22/4884/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/CU CPT 22/4884/10/10 mg

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Tocris

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4884/10

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4000-520-616

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Description:SelectiveTLR1/2inhibitor

ChemicalName:3,4,6-Trihydroxy-2-methoxy-5-oxo-5H-benzocycloheptene-8-carboxylicacidhexylester

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivetoll-likereceptor1/2(TLR1/2)inhibitor(IC₅₀=0.58μM).ExhibitsnoactivityatTLR2/TLR6,TLR3,TLR4andTLR7orapanelof10representativekinases.InhibitsthereleaseofproinflammatorycytokinesTNF-αandIL-1β.

LicensingInformation

SoldunderlicensefromtheUniversityofColorado

TechnicalData

M.Wt	362.37
Formula	C₁₉H₂₂O₇
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1416324-85-0
PubChemID	71503400
InChIKey	UBQFTTUFRSSOHE-UHFFFAOYSA-N
Smiles	O=C1C(O)=CC(C(OCCCCCC)=O)=CC2=C1C(O)=C(O)C(OC)=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	36.24	100
	ethanol	18.12	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight362.37.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.76mL	13.8mL	27.6mL
5mM	0.55mL	2.76mL	5.52mL
10mM	0.28mL	1.38mL	2.76mL
50mM	0.06mL	0.28mL	0.55mL

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