进口试剂Tocris直采正品Tocris Bioscience生物试剂1,Tocris/CU-T12-9/5414/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/CU-T12-9/5414/50/50 mg

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Tocris

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5414/50

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4000-520-616

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Description:PotentTLR1/2agoNIST

ChemicalName:N-Methyl-4-nitro-2-(4-(4-trifluoromethyl)phenyl)-1H-imidazol-1-yl)aniline

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentTLR1/2agonist(EC₅₀=52.9nM).ActivatestheNF-κBpathwayandupregulatesproinflammatorycytokinesinvitro.AlsoenhancesTLR1andTLR2dimerization.

LicensingInformation

SoldunderlicensefromtheUniversityofColorado

CompoundLibraries

CU-T12-9isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	362.31
Formula	C₁₇H₁₃F₃N₄O₂
Storage	Storeat+4°C
Purity	≥99%(HPLC)
PubChemID	91826088
InChIKey	LITXVDAFEYLWQE-UHFFFAOYSA-N
Smiles	CNC1=CC=C([N+]([O-])=O)C=C1N2C=C(C3=CC=C(C(F)(F)F)C=C3)N=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	36.23	100
	ethanol	7.25	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight362.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.76mL	13.8mL	27.6mL
5mM	0.55mL	2.76mL	5.52mL
10mM	0.28mL	1.38mL	2.76mL
50mM	0.06mL	0.28mL	0.55mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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