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Description:PotentandselectiveS1P4agoNIST
ChemicalName:2-Chloro-3-[2-(2,4-dichlorophenoxy)ethoxy]-6-(fluoromethyl)pyridine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potentsphingosine-1-phosphatereceptor4(S1P4)agonist(EC50=45nM).DisplaysnoactivityatotherS1Preceptorsubtypes(S1P1-3andS1P5)atconcentrationsupto25μM.
CompoundLibraries
CYM50260isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 350.6 |
Formula | C14H11Cl3FNO2 |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 1355026-60-6 |
PubChemID | 44620894 |
InChIKey | FHPOTBQOUBMMCI-UHFFFAOYSA-N |
Smiles | ClC1=CC(Cl)=C(OCCOC2=CC=C(CF)N=C2Cl)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 35.06 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight350.6.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.85mL | 14.26mL | 28.52mL |
5mM | 0.57mL | 2.85mL | 5.7mL |
10mM | 0.29mL | 1.43mL | 2.85mL |
50mM | 0.06mL | 0.29mL | 0.57mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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