Tocris试剂采购 Tocris神经传递素,Tocris/CYM 50308/4678/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/CYM 50308/4678/10/10 mg

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Tocris

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4678/10

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4000-520-616

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Description:PotentandselectiveS1P₄agoNIST

ChemicalName:(2Z,5Z)-5-[[1-(2,4-Difluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylene]-2-[(2-methoxyethyl)imino]-3-methyl-4-thiazolidinone

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivesphingosine-1-phosphatereceptor4(S1P₄)agonist(EC₅₀valuesare56nMand2100nMforS1P₄andS1P₅receptors,respectively).DisplaysnoactivityatS1P₁,S1P₂andS1P₃receptorsatconcentrationsupto25μM.

TechnicalData

M.Wt	405.46
Formula	C₂₀H₂₁F₂N₃O₂S
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1345858-76-5
PubChemID	49835928
InChIKey	BKQZKTRCUAWRHT-ONBPWHQPSA-N
Smiles	FC1=CC(F)=C(N2C(C)=CC(/C=C3S/C(N(C)C3=O)=NCCOC)=C2C)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	4.05	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight405.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.47mL	12.33mL	24.66mL
5mM	0.49mL	2.47mL	4.93mL
10mM	0.25mL	1.23mL	2.47mL
50mM	0.05mL	0.25mL	0.49mL

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