Tocris公司代理生物计划 Tocris Bioscience现货代理,Tocris/CYM 5442 hydrochloride/3601/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/CYM 5442 hydrochloride/3601/10/10 mg

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Tocris/CYM 5442 hydrochloride/3601/10/10 mg

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Tocris

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3601/10

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Description:SelectiveS1P₁receptoragoNIST

ChemicalName:2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxADIazol-3-yl)-2,3-dihydro-1H-inden-1-ylamino)ethanolhydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveS1P₁agonistinvitro(EC₅₀=1.35nM).ActivatesS1P₁-mediatedp42/p44MAPKphosphorylationinCHO-K1cellstransfectedwithS1P₁.Inducesacutelymphopeniainmice.Brainpenetrant.

TechnicalData

M.Wt	445.94
Formula	C₂₃H₂₇N₃O₄.HCl
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1094042-01-9
PubChemID	90488865
InChIKey	KMZLVDAVGXYZDA-UHFFFAOYSA-N
Smiles	OCCNC3CCC(C3=CC=C4)=C4C1=NOC(C2=CC(OCC)=C(OCC)C=C2)=N1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	44.59	100
	water	4.46	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight445.94.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.24mL	11.21mL	22.42mL
5mM	0.45mL	2.24mL	4.48mL
10mM	0.22mL	1.12mL	2.24mL
50mM	0.04mL	0.22mL	0.45mL

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