Tocris一级代理 Tocris离子通道调控剂,Tocris/Cl-4AS-1/3812/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/Cl-4AS-1/3812/50/50 mg

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Tocris

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3812/50

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4000-520-616

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Description:SteroidalandrogenreceptoragoNIST

ChemicalName:(4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)-N-(2-Chlorophenyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1,4,6a-trimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentsteroidalandrogenreceptoragonist(IC₅₀=12nM).Mimicstheactionof5α-dihydrotestosterone(DHT).Transactivatesthemousemammarytumorvirus(MMTV)promoter;repressesMMP1promoteractivity.Inhibits5α-reductasetypeIandII(IC₅₀valuesare6and10nMrespectively).

TechnicalData

M.Wt	441.01
Formula	C₂₆H₃₃ClN₂O₂
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	188589-66-4
PubChemID	90488881
InChIKey	CTVXDPDUOKQBKZ-BLIBDJTASA-N
Smiles	O=[C@](NC5=CC=CC=C5Cl)[C@H]4CC[C@@]3([H])[C@]2([H])CCC1N(C)C(C=C[C@@](C)1[C@]([H])2CC[C@]34C)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	4.41	10
	ethanol	4.41	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight441.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.27mL	11.34mL	22.68mL
5mM	0.45mL	2.27mL	4.54mL
10mM	0.23mL	1.13mL	2.27mL
50mM	0.05mL	0.23mL	0.45mL

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