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Description:HighlypotentH3antagoNISTandH4partialagonist
AlternativeNames:VUF9153
ChemicalName:N-(4-Chlorobenzyl)-S-[3-(4(5)-imidazolyl)propyl]isothioureadihydrobromide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
AnextremelypotenthistamineH3antagonist/inverseagonist(pA2=9.93).AlsodisplayspartialagonistactivityatH4receptors;induceseosinophilshapechangewithanEC50of3nM.AlsoavailableaspartoftheHistamineH3ReceptorTocriset™.
LicensingInformation
SoldwiththepermissionofSCI,Amsterdam
TechnicalData
M.Wt | 470.65 |
Formula | C14H17ClN4S.2HBr |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 145231-35-2 |
PubChemID | 11213569 |
InChIKey | JIJQPEZAVLJZBO-UHFFFAOYSA-N |
Smiles | Br.Br.ClC1=CC=C(CNC(=N)SCCCC2=CNC=N2)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solubility | Solubleto100mMinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight470.65.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.12mL | 10.62mL | 21.25mL |
5mM | 0.42mL | 2.12mL | 4.25mL |
10mM | 0.21mL | 1.06mL | 2.12mL |
50mM | 0.04mL | 0.21mL | 0.42mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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