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Description:PotentandselectiveH3receptorantagoNIST
ChemicalName:N,N-Dimethyl-con-5-enin-3-amine
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
PotentandselectivehistamineH3receptorantagonist(pKivaluesare7.61and8.27atratandhumanH3receptorsrespectively).Asteroidalalkaloidthatdisplaysinvitroantiplasmodialactivity(IC50=1.04μM).Alsohashighaffinityforα2Cadrenoceptors(pKi=7.98).
TechnicalData
M.Wt | 356.59 |
Formula | C24H40N2 |
Storage | StoreatRT |
CASNumber | 546-06-5 |
PubChemID | 441082 |
InChIKey | GPLGAQQQNWMVMM-MYAJQUOBSA-N |
Smiles | [H][C@@]23CC=C1C[C@@H](N(C)C)CC[C@@](C)1[C@]([H])2CC[C@@]45[C@]([H])3CC[C@@]([H])4[C@H](C)N(C)C5 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 17.85 | 50mMwithgentlewarming | |
ethanol | 17.85 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight356.59.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.8mL | 14.02mL | 28.04mL |
5mM | 0.56mL | 2.8mL | 5.61mL |
10mM | 0.28mL | 1.4mL | 2.8mL |
50mM | 0.06mL | 0.28mL | 0.56mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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