BiologicalActivity
Selectiveagonistofhydroxycarboxylicacidreceptor1(HCA1,alsoknownasGPR81)(EC50~150μM).Inhibitslipolysisinwild-typemouseADIpocytes.DisplaysminimalactivityatHCA2(atconcentrations>10mM)andnoactivityatHCA3,freefattyacidreceptor(FFAR)2orFFAR3.
TechnicalData
| M.Wt | 154.12 |
| Formula | C7H6O4 |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 99-10-5 |
| PubChemID | 7424 |
| InChIKey | UYEMGAFJOZZIFP-UHFFFAOYSA-N |
| Smiles | OC1=CC(O)=CC(C(O)=O)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 15.41 | 100 | |
| ethanol | 15.41 | 100 | |
| water | 15.41 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight154.12.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 6.49mL | 32.44mL | 64.88mL |
| 5mM | 1.3mL | 6.49mL | 12.98mL |
| 10mM | 0.65mL | 3.24mL | 6.49mL |
| 50mM | 0.13mL | 0.65mL | 1.3mL |
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