BiologicalActivity
Selectivearylhydrocarbonreceptor(AHR)modulator(SAhRM).SuppressesexpressionofCD55andCD46inducedbyIL-1βinaninflammatorytumorcellmicroenvironment;exhibitsnoeffectonbasalCD55orCD46expression.
TechnicalData
| M.Wt | 332.35 |
| Formula | C21H16O4 |
| Storage | Storeat+4°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 14756-24-2 |
| PubChemID | 276138 |
| InChIKey | QDZQDIUUJDAORK-UHFFFAOYSA-N |
| Smiles | O=C2C=C(C4=CC(OC)=C(OC)C=C4)OC1=C3C(C=CC=C3)=CC=C12 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 1.66 | 5 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight332.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.01mL | 15.04mL | 30.09mL |
| 5mM | 0.6mL | 3.01mL | 6.02mL |
| 10mM | 0.3mL | 1.5mL | 3.01mL |
| 50mM | 0.06mL | 0.3mL | 0.6mL |
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