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Description:GPR3agoNIST;alsoinhibitsNOSandNADPHoxidases
AlternativeNames:DPI
ChemicalName:[1,1'-Biphenyl]-2,2'-diyliodoniumchloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
GPR3agonist(EC50=1μM);activatesadenylatecyclasethroughGPR3butnotGPR6orGPR12.AlsoinducesCa2+mobilizationandβ-arrestinreceptorinternalization.Bindsstronglytoflavoproteins;inhibitsseveralenzymes,includingNOsynthase,NADPHoxidasesandNADPHcytochromeP450oxidoreductase.Alsoinhibitsplateletaggregation.
TechnicalData
M.Wt | 314.55 |
Formula | C12H8ClI |
Storage | Desiccateat-20°C |
Purity | ≥99%(HPLC) |
CASNumber | 4673-26-1 |
PubChemID | 2733504 |
InChIKey | FCFZKAVCDNTYID-UHFFFAOYSA-M |
Smiles | [Cl-].c1c2c3ccccc3[i+]c2ccc1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 3.14 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight314.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.18mL | 15.9mL | 31.79mL |
5mM | 0.64mL | 3.18mL | 6.36mL |
10mM | 0.32mL | 1.59mL | 3.18mL |
50mM | 0.06mL | 0.32mL | 0.64mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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