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Tocris/Diphenyleneiodonium chloride/0504/50/50 mg
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Tocris/Diphenyleneiodonium chloride/0504/50/50 mg
品牌 / 
Tocris
货号 / 
0504/50
美元价:
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数    量:
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4000-520-616
Description:GPR3agoNIST;alsoinhibitsNOSandNADPHoxidases
AlternativeNames:DPI
ChemicalName:[1,1'-Biphenyl]-2,2'-diyliodoniumchloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

GPR3agonist(EC50=1μM);activatesadenylatecyclasethroughGPR3butnotGPR6orGPR12.AlsoinducesCa2+mobilizationandβ-arrestinreceptorinternalization.Bindsstronglytoflavoproteins;inhibitsseveralenzymes,includingNOsynthase,NADPHoxidasesandNADPHcytochromeP450oxidoreductase.Alsoinhibitsplateletaggregation.

TechnicalData

M.Wt314.55
FormulaC12H8ClI
StorageDesiccateat-20°C
Purity≥99%(HPLC)
CASNumber4673-26-1
PubChemID2733504
InChIKeyFCFZKAVCDNTYID-UHFFFAOYSA-M
Smiles[Cl-].c1c2c3ccccc3[i+]c2ccc1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO3.1410

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight314.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.18mL15.9mL31.79mL
5mM0.64mL3.18mL6.36mL
10mM0.32mL1.59mL3.18mL
50mM0.06mL0.32mL0.64mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet