Tocris产品目录价格美国Tocris Bioscience公司,Tocris/ER 50891/3823/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/ER 50891/3823/50/50 mg

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Tocris

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3823/50

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4000-520-616

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Description:SelectiveRARαantagoNIST

ChemicalName:4-[5-[8-(1-Methylethyl)-4-phenyl-2-quinolinyl]-1H-pyrrolo-2-benzoicacid

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

AntagonistofRARαreceptors(IC₅₀=31.2nM).DisplaysselectiveaffinityforRARα(relativeIC₅₀valuesare1.8,432and535nMforRARα,RARγandRARβrespectively).

CompoundLibraries

ER50891isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	432.51
Formula	C₂₉H₂₄N₂O₂
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	187400-85-7
PubChemID	10094345
InChIKey	LSGNKLDHMQVTEK-UHFFFAOYSA-N
Smiles	CC(C)C1=C2C(C(C3=CC=CC=C3)=CC(C4=CC=C(C5=CC=C(C(O)=O)C=C5)N4)=N2)=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	43.25	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight432.51.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.31mL	11.56mL	23.12mL
5mM	0.46mL	2.31mL	4.62mL
10mM	0.23mL	1.16mL	2.31mL
50mM	0.05mL	0.23mL	0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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