Tocris离子通道调控剂 Tocris抗体,Tocris/Edaglitazone/4784/50/50 mg,摇床,Tocris,Bio-Techne,,50 mg蚂蚁淘商城

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Tocris/Edaglitazone/4784/50/50 mg

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Tocris

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4784/50

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4000-520-616

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Description:PotentandselectivePPARγagoNIST;antidiabetic

AlternativeNames:R483,BM131258

ChemicalName:5-[[4-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethoxy]benzo[b]thien-7-yl]methyl]-2,4-thiazolidinedione

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectivePPARγagonist(EC₅₀valuesare35.6and1053nMforPPARγandPPARαcofactorrecruitmentrespectively.Enhancesinsulinsensitivityinobese,butnotlean,rats.Antidiabeticandorallybioavailable.

CompoundLibraries

EdaglitazoneisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	464.56
Formula	C₂₄H₂₀N₂O₄S₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	213411-83-7
PubChemID	9825701
InChIKey	HAAXAFNSRADSMK-UHFFFAOYSA-N
Smiles	CC(OC(C5=CC=CC=C5)=N4)=C4CCOC(C3=C2SC=C3)=CC=C2CC1C(NC(S1)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

Solubility	Solubleto100mMinDMSO

Solubility

Solubleto100mMinDMSO

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight464.56.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.15mL	10.76mL	21.53mL
5mM	0.43mL	2.15mL	4.31mL
10mM	0.22mL	1.08mL	2.15mL
50mM	0.04mL	0.22mL	0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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