BiologicalActivity
Endogenousestrogenreceptor(ER)agonist(Kivaluesare0.12and0.13nMforERαandERβrespectively).AlsohighaffinityligandatmembraneestrogenGPR30receptors.α-Estradiol(Cat.No.2823)alsoavailable.
TechnicalData
| M.Wt | 272.38 |
| Formula | C18H24O2 |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 50-28-2 |
| PubChemID | 5757 |
| InChIKey | VOXZDWNPVJITMN-ZBRFXRBCSA-N |
| Smiles | [H][C@@]23CCC1=CC(O)=CC=C1[C@]([H])2CC[C@@]4(C)[C@]([H])3CC[C@@H]4O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 27.24 | 100 | |
| ethanol | 20.43 | 75 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight272.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.67mL | 18.36mL | 36.71mL |
| 5mM | 0.73mL | 3.67mL | 7.34mL |
| 10mM | 0.37mL | 1.84mL | 3.67mL |
| 50mM | 0.07mL | 0.37mL | 0.73mL |
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