中国Tocris公司 Tocris Bioscience一级代理,Tocris/Fexaramine/2563/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/Fexaramine/2563/10/10 mg

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Tocris

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2563/10

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Description:Potent,selectivefarnesoidXreceptor(FXR)agoNIST

ChemicalName:3-[3-[(Cyclohexylcarbonyl)-[[4'-(dimethylamino)-[1,1'-biphenyl]-4-yl]methyl]amino]phenyl]-2-propenoicacidmethylester

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selectivefarnesoidXreceptoragonist(EC₅₀=25nM).DisplaysnoactivityathRXRα,hPPARα,hPPARγ,hPPARδ,mPXR,hPXR,hLXRα,hTRβ,hRARβ,mCAR,mERRγandhVDRreceptors.

CompoundLibraries

FexaramineisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	496.64
Formula	C₃₂H₃₆N₂O₃
Storage	Desiccateat+4°C
Purity	≥97%(HPLC)
CASNumber	574013-66-4
PubChemID	5326713
InChIKey	VLQTUNDJHLEFEQ-KGENOOAVSA-N
Smiles	O=C(C3CCCCC3)N(CC2=CC=C(C4=CC=C(N(C)C)C=C4)C=C2)C1=CC(/C=C/C(OC)=O)=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	49.66	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight496.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.01mL	10.07mL	20.14mL
5mM	0.4mL	2.01mL	4.03mL
10mM	0.2mL	1.01mL	2.01mL
50mM	0.04mL	0.2mL	0.4mL

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