美国Tocris公司 Tocris化合物筛选文库,Tocris/Fluorobexarotene/4064/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/Fluorobexarotene/4064/10/10 mg

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Tocris

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4064/10

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4000-520-616

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Description:RXRagoNIST

ChemicalName:2-Fluoro-4-[1-(5-,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoicacid

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

RXRagonist(K_i=12nM;EC₅₀=43nMatRXRαreceptors).DisplayssimilarRARagonistactivitytobexarotene;exhibitsanapparentRXRbindingaffinity75%greaterthanbexarotene.

LicensingInformation

ManufacturedandsoldunderlicensefromArizonaStateUniversity-PatentPending

TechnicalData

M.Wt	366.47
Formula	C₂₄H₂₇FO₂
Storage	Storeat+4°C
Purity	≥97%(HPLC)
CASNumber	1190848-23-7
PubChemID	25195496
InChIKey	LWKAWHRSPCHMPJ-UHFFFAOYSA-N
Smiles	CC(C(C(C3=CC=C(C(O)=O)C(F)=C3)=C)=C2)=CC1=C2C(C)(C)CCC(C)1C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	36.65	100
	ethanol	9.16	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight366.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.73mL	13.64mL	27.29mL
5mM	0.55mL	2.73mL	5.46mL
10mM	0.27mL	1.36mL	2.73mL
50mM	0.05mL	0.27mL	0.55mL

ProductDatasheets

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