BiologicalActivity
ProstaglandinF2α(FP)receptoragonist(Ki=49.9nM;EC50=2.4nM).StimulatesintracellularcalciummobilizationinclonedhumanocularFPreceptors,ratA7r5cellsandmouse3T3cells(EC50valuesare17.5,19.1and37.3nMrespectively).AnalogofprostaglandinF2α.Isopropylestertravaprost(Cat.No.4218)alsoavailable.
TechnicalData
| M.Wt | 458.47 |
| Formula | C23H29F3O6 |
| Storage | Storeat-20°C |
| Purity | ≥95%(HPLC) |
| CASNumber | 54276-17-4 |
| PubChemID | 5311100 |
| InChIKey | WWSWYXNVCBLWNZ-QIZQQNKQSA-N |
| Smiles | O[C@@H]1C[C@H](O)[C@H](C/C=CCCCC(O)=O)[C@H]1/C=C/[C@@H](O)COC2=CC=CC(C(F)(F)F)=C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleinethanol(suppliedpre-dissolvedinanhydrousethanol,10mg/ml) |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight458.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.18mL | 10.91mL | 21.81mL |
| 5mM | 0.44mL | 2.18mL | 4.36mL |
| 10mM | 0.22mL | 1.09mL | 2.18mL |
| 50mM | 0.04mL | 0.22mL | 0.44mL |
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