Tocris型号参数规格 Tocris GPCR ligands,Tocris/GR 55562 dihydrochloride/1054/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/GR 55562 dihydrochloride/1054/50/50 mg

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Tocris/GR 55562 dihydrochloride/1054/50/50 mg

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Tocris

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1054/50

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4000-520-616

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Description:5-HT_1BantagoNIST

ChemicalName:3-[3-(Dimethylamino)propyl]-4-hydroxy-N-[4-(4-pyridinyl)phenyl]benzamidedihydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Aselectivecompetitive5-HT_1B(5-HT_1Dβ)silentantagonistwithpK_Bvaluesof7.3and6.3forhumancloned5-HT_1Band5-HT_1Dreceptorsrespectivelyandonlyweakbindingatanumberofother5-HTsubtypes.

LicensingInformation

SoldwiththepermissionofGlaxoSmithKline

TechnicalData

M.Wt	448.39
Formula	C₂₃H₂₅N₃O₂.2HCl
Storage	Desiccateat+4°C
Purity	≥98%(HPLC)
CASNumber	159533-25-2
PubChemID	56972159
InChIKey	KBKWJHYQFQONBJ-UHFFFAOYSA-N
Smiles	Cl.Cl.CN(C)CCCC1=CC(=CC=C1O)C(=O)NC1=CC=C(C=C1)C1=CC=NC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

Solubility	Solubleto100mMinwater

Solubility

Solubleto100mMinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight448.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.23mL	11.15mL	22.3mL
5mM	0.45mL	2.23mL	4.46mL
10mM	0.22mL	1.12mL	2.23mL
50mM	0.04mL	0.22mL	0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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TechnicalData

SolubilityData

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