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Tocris/GSK 0660/3433/10/10 mg
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Tocris/GSK 0660/3433/10/10 mg
品牌 / 
Tocris
货号 / 
3433/10
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4000-520-616
Description:SelectivePPARδantagoNIST
ChemicalName:3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectivePPARδantagonist(IC50valuesare0.155,>10and10μMatPPARδ,PPARαandPPARγrespectively).Exhibitsinverseagonisteffectswhenadministeredbyitself.

CompoundLibraries

GSK0660isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt418.49
FormulaC19H18N2O5S2
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber1014691-61-2
PubChemID46233311
InChIKeyNDFKBGWLUHKMFY-UHFFFAOYSA-N
SmilesO=S(NC1=C(OC)C=C(NC3=CC=CC=C3)C=C1)(C2=C(C(OC)=O)SC=C2)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO41.85100
ethanol4.1810

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight418.49.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.39mL11.95mL23.9mL
5mM0.48mL2.39mL4.78mL
10mM0.24mL1.19mL2.39mL
50mM0.05mL0.24mL0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet