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Description:Selectiveα1DantagoNIST
ChemicalName:8-[2-[4-(methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dionedihydrochloride
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
5-HT1Apartialagonistandhighaffinityα1Dadrenoceptorantagonist(Kivaluesare2,800and600nMatclonedratα1D,ratα1Aandhamsterα1Breceptorsrespectively).Alsoavailableaspartoftheα1-AdrenoceptorTocriset™.
TechnicalData
M.Wt | 458.42 |
Formula | C22H31N3O3.2HCl |
Storage | StoreatRT |
CASNumber | 21102-95-4 |
PubChemID | 24744861 |
InChIKey | HZRPUQURUAXOHB-UHFFFAOYSA-N |
Smiles | O=C1CC4(CCCC4)CC(N1CCN(CC3)CCN3C2=CC=CC=C2OC)=O.Cl.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solubility | Solubleto100mMinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight458.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.18mL | 10.91mL | 21.81mL |
5mM | 0.44mL | 2.18mL | 4.36mL |
10mM | 0.22mL | 1.09mL | 2.18mL |
50mM | 0.04mL | 0.22mL | 0.44mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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