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Description:Selective5-HT1AagoNIST.Enantiomerof8-Hydroxy-DPAThydrobromide(Cat.No.0529)
ChemicalName:(2R)-(+)-8-Hydroxy-2-(di-n-propylamino)tetralinhydrobromide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Full5-HT1ASEROtoninreceptoragonist;moreactiveenantiomer.Reduceshippocampal5-HTlevelsfollowingsystemicadministrationinratsinvivo.Moreactiveenantiomerof8-Hydroxy-DPAThydrobromide(Cat.No.0529).7-Hydroxy-DPAThydrobromide(Cat.No.0706)alsoavailable.
TechnicalData
M.Wt | 328.29 |
Formula | C16H25NO.HBr |
Storage | Desiccateat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 78095-19-9 |
PubChemID | 11957570 |
InChIKey | BATPBOZTBNNDLN-PFEQFJNWSA-N |
Smiles | Br.CCCN(CCC)[C@@H]1CCC2=CC=CC(O)=C2C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 24.62 | 75 | |
water | 24.62 | 75 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight328.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.05mL | 15.23mL | 30.46mL |
5mM | 0.61mL | 3.05mL | 6.09mL |
10mM | 0.3mL | 1.52mL | 3.05mL |
50mM | 0.06mL | 0.3mL | 0.61mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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