Tocris产品促销进口Tocris Bioscience现货,Tocris/(<em>S</em>)-WAY 100135 dihydrochloride/1253/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/(<em>S</em>)-WAY 100135 dihydrochloride/1253/50/50 mg

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Tocris/(S)-WAY 100135 dihydrochloride/1253/50/50 mg

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Tocris

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1253/50

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4000-520-616

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Description:Potent,selective5-HT_1AantagoNIST

ChemicalName:(S)-N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamidedihydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selective5-HT_1Areceptorantagonist(IC₅₀=15nM).Selectiveover5-HT_1B,_1C,₂,α₁,α₂andD₂receptors(IC₅₀>1000nM).Centrallyactiveonsystemicadministration.

LicensingInformation

SoldwiththepermissionofWyeth-AyerstResearch,USPatent4,988,814

TechnicalData

M.Wt	468.47
Formula	C₂₄H₃₃N₃O₂.2HCl
Storage	Desiccateat+4°C
Purity	≥99%(HPLC)
CASNumber	149007-54-5
PubChemID	6604839
InChIKey	NYZFUZCCDOSQBG-AWEZNQCLSA-N
Smiles	O=C(NC(C)(C)C)[C@@]([C@]3=CC=CC=C3)([H])CN(CC2)CCN2C1=C(OC)C=CC=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	46.85	100
	water	2.34	5mMwithgentlewarming
	water	4.68	10mMwithsonication

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight468.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.13mL	10.67mL	21.35mL
5mM	0.43mL	2.13mL	4.27mL
10mM	0.21mL	1.07mL	2.13mL
50mM	0.04mL	0.21mL	0.43mL

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