Tocris现货代理进口Tocris Bioscience现货,Tocris/WAY 100635 maleate/4380/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/WAY 100635 maleate/4380/50/50 mg

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Tocris

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4380/50

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4000-520-616

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Description:Potent,5-HT_1AsilentantagoNIST.AlsoD₄agonist

ChemicalName:N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamidemaleate

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,silentantagonistof5-HT_1Areceptors(IC₅₀=2.2nM;K_i=0.84nMforrat5-HT_1Areceptors).Displays100-foldselectivityfor5-HT_1Aoverother5-HTsubtypes.AlsoexhibitsagonistactivityatdopamineD₄receptors.

TechnicalData

M.Wt	538.64
Formula	C₂₅H₃₄N₄O₂.C₄H₄O₄
Storage	DesiccateatRT
Purity	≥99%(HPLC)
CASNumber	634908-75-1
PubChemID	11957721
InChIKey	XIGAHNVCEFUYOV-BTJKTKAUSA-N
Smiles	O=C(C4CCCCC4)N(C3=NC=CC=C3)CCN(CC2)CCN2C1=C(OC)C=CC=C1.O=C(C=C/C(O)=O)O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	water	13.47	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight538.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.86mL	9.28mL	18.57mL
5mM	0.37mL	1.86mL	3.71mL
10mM	0.19mL	0.93mL	1.86mL
50mM	0.04mL	0.19mL	0.37mL

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