Tocris批发，产品货源 Tocris神经传递素,Tocris/3-MPPI/0581/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/3-MPPI/0581/50/50 mg

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Tocris

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0581/50

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4000-520-616

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Description:α₁ligand

ChemicalName:2-[(4-Phenylpiperazin-1-yl)methyl]-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Verypotentligandforα₁sites(K_ifordisplacementofprazosin=0.2nM).Displaysdifferentbindingpropertiesforeachα1subtype(pK_ivaluesare8.74,9.44and9.57forα_1B,α_1Dandα_1Aadrenoceptorsrespectively).Alsobindsto5-HT_1Asites(K_i=50nM).

TechnicalData

M.Wt	419.48
Formula	C₂₃H₂₅N₅O₃
Storage	StoreatRT
CASNumber	133399-65-2
PubChemID	4013695
InChIKey	AQASGOHUMGAWJJ-UHFFFAOYSA-N
Smiles	COC1=C(C=CC=C1)N1CCN(CCN2C(=O)NC3=C(NC4=CC=CC=C34)C2=O)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	4.19	10mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight419.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.38mL	11.92mL	23.84mL
5mM	0.48mL	2.38mL	4.77mL
10mM	0.24mL	1.19mL	2.38mL
50mM	0.05mL	0.24mL	0.48mL

ProductDatasheets

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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