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Description:CB2selectiveantagoNIST/inverseagonist
ChemicalName:6-Iodo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl](4-methoxyphenyl)methanone
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
CB2antagonist/inverseagonist(Ki=31.2nM)thatdisplays165-foldselectivityoverCB1receptors.Behavesasaweakpartial/inverseagonistatCB1receptors.
TechnicalData
| M.Wt | 504.37 |
| Formula | C23H25IN2O3 |
| Storage | Desiccateat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 164178-33-0 |
| PubChemID | 4302963 |
| InChIKey | JHOTYHDSLIUKCJ-UHFFFAOYSA-N |
| Smiles | COC1=CC=C(C=C1)C(=O)C1=C(C)N(CCN2CCOCC2)C2=CC(I)=CC=C12 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 50.44 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight504.37.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.98mL | 9.91mL | 19.83mL |
| 5mM | 0.4mL | 1.98mL | 3.97mL |
| 10mM | 0.2mL | 0.99mL | 1.98mL |
| 50mM | 0.04mL | 0.2mL | 0.4mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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