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Description:CB1/CB2receptorpartialagoNIST
ChemicalName:3-[2-Cyano-3-(trifluoromethyl)phenoxy]phenyl4,4,4-trifluoro-1-butanesulfonicacidester
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
NovelCB1/CB2receptorpartialagonist(Kivaluesare48.3and45.5nMathumanCB1andCB2receptorsrespectively).OrallyactiveCB1agonistinvivo.Displaysanti-hyperalgesicandantiallodynicpropertiesinratmodelsofchronicneuropathicandinflammatorypain.
LicensingInformation
SoldforresearchpurposesunderagreementfromBayer
TechnicalData
M.Wt | 453.35 |
Formula | C18H13F6NO4S |
Storage | Storeat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 406205-74-1 |
PubChemID | 10479060 |
InChIKey | LWUSZIVDPJPVBW-UHFFFAOYSA-N |
Smiles | FC(F)(F)CCCS(=O)(=O)OC1=CC(OC2=CC=CC(=C2C#N)C(F)(F)F)=CC=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 45.34 | 100 | |
ethanol | 45.34 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight453.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.21mL | 11.03mL | 22.06mL |
5mM | 0.44mL | 2.21mL | 4.41mL |
10mM | 0.22mL | 1.1mL | 2.21mL |
50mM | 0.04mL | 0.22mL | 0.44mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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