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Description:PotentdualCB1/CB2agoNIST
ChemicalName:1-Naphthalenyl[4-(pentyloxy)-1-naphthalenyl]methanone
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potent,orallyactiveCB1/CB2receptoragonistwithlimitedbrainpenetration(EC50valuesare6.1and27.9nMforCB1andCB2receptorsrespectively).DisplaysantihyperalgesicactivityinaratmodelofneuropathicpainwithnoCNSsideeffects.
TechnicalData
| M.Wt | 368.47 |
| Formula | C26H24O2 |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 432047-72-8 |
| PubChemID | 9799417 |
| InChIKey | RSUMDJRTAFBISX-UHFFFAOYSA-N |
| Smiles | O=C(C3=CC=CC4=C3C=CC=C4)C2=CC=C(OCCCCC)C1=CC=CC=C12 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 36.85 | 100 | |
| ethanol | 18.42 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight368.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.71mL | 13.57mL | 27.14mL |
| 5mM | 0.54mL | 2.71mL | 5.43mL |
| 10mM | 0.27mL | 1.36mL | 2.71mL |
| 50mM | 0.05mL | 0.27mL | 0.54mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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