BiologicalActivity
Potentandselectiveμ-opioidreceptoragonist(Kivaluesare7.0,151and470nMforμ-,δ-andκ-opioidreceptorsrespectively).Displaysantinociceptiveactivityinvivo.
TechnicalData
| M.Wt | 528.59 |
| Formula | C22H28N2O.C6H8O7 |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 990-73-8 |
| PubChemID | 13810 |
| InChIKey | IVLVTNPOHDFFCJ-UHFFFAOYSA-N |
| Smiles | O=C(O)C(O)(CC(O)=O)CC(O)=O.O=C(CC)N(C3=CC=CC=C3)C1CCN(CCC2=CC=CC=C2)CC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| water | 21.14 | 40 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight528.59.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.89mL | 9.46mL | 18.92mL |
| 5mM | 0.38mL | 1.89mL | 3.78mL |
| 10mM | 0.19mL | 0.95mL | 1.89mL |
| 50mM | 0.04mL | 0.19mL | 0.38mL |
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