Tocris中国试剂购买网站美国Tocris Bioscience公司,Tocris/GP 1a/2764/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/GP 1a/2764/50/50 mg

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Tocris

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2764/50

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4000-520-616

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Description:HighlyselectiveCB₂agoNIST

ChemicalName:N-(Piperidin-1-yl)-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3-carboxamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighlyselectiveCB₂receptoragonist;K_ivaluesare0.037and363nMforCB₂andCB₁receptorsrespectively.IncreasesP-ERK1/2expressioninHL-60cellsinvitro.MorerecentlyshowntobeCB₂receptorinverseagonist/antagonistincAMP,GTPγSandβ-arrestinrecruitmentassays.

TechnicalData

M.Wt	441.35
Formula	C₂₃H₂₂Cl₂N₄O
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	511532-96-0
PubChemID	10252734
InChIKey	FNOMTMVRTBHRET-UHFFFAOYSA-N
Smiles	CC1=CC2=C(C=C1)C1=C(C2)C(=NN1C1=CC=C(Cl)C=C1Cl)C(=O)NN1CCCCC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	44.13	100
	ethanol	44.13	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight441.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.27mL	11.33mL	22.66mL
5mM	0.45mL	2.27mL	4.53mL
10mM	0.23mL	1.13mL	2.27mL
50mM	0.05mL	0.23mL	0.45mL

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