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Description:Potent,selectiveCB2agoNIST
AlternativeNames:COR167
ChemicalName:N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinoline-3-carboxamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
PotentandselectiveCB2receptoragonist(Kivaluesare6.3nMand1.2μMforCB2andCB1receptorsrespectively).Displaysanalgesicactivityintheformalintestinmice.
TechnicalData
| M.Wt | 434.61 |
| Formula | C28H38N2O2 |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 1048038-90-9 |
| PubChemID | 25034551 |
| InChIKey | KUMKLUDNETVLDS-UHFFFAOYSA-N |
| Smiles | O=C(C4=CN(CCCCC)C5=C(C=C(C(C)C)C=C5)C4=O)NC12CC(C3)CC(CC3C2)C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 10.87 | 25 | |
| ethanol | 21.73 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight434.61.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.3mL | 11.5mL | 23.01mL |
| 5mM | 0.46mL | 2.3mL | 4.6mL |
| 10mM | 0.23mL | 1.15mL | 2.3mL |
| 50mM | 0.05mL | 0.23mL | 0.46mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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