Tocris中国采购 Tocris多肽,Tocris/(<em>Z</em>)-4-Hydroxytamoxifen/3412/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/(<em>Z</em>)-4-Hydroxytamoxifen/3412/50/50 mg

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Tocris/(Z)-4-Hydroxytamoxifen/3412/50/50 mg

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Tocris

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3412/50

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4000-520-616

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Description:Metaboliteoftamoxifen(Cat.No.0999)

AlternativeNames:4-OH-TAM

ChemicalName:4-[(1Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

EstrogenreceptorantagoNIST.Tamoxifen(Cat.No.0999)metabolite;exhibitsgreaterpotencythantheparentcompound.Chemotherapeuticagent.Alsoactivatesintein-linkedinactiveCas9,reducingoff-targetCRISPR-mediatedgeneediting;systemhas~25-foldhigherspecificitythanwtCas9.

TechnicalData

M.Wt	387.51
Formula	C₂₆H₂₉NO₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	68047-06-3
PubChemID	449459
InChIKey	TXUZVZSFRXZGTL-QPLCGJKRSA-N
Smiles	CCC(C3=CC=CC=C3)=C(C2=CC=C(OCCN(C)C)C=C2)/C1=CC=C(O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	38.75	100
	ethanol	19.38	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight387.51.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.58mL	12.9mL	25.81mL
5mM	0.52mL	2.58mL	5.16mL
10mM	0.26mL	1.29mL	2.58mL
50mM	0.05mL	0.26mL	0.52mL

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