Tocris中国试剂购买网站 Tocris Bioscience型号参数规格,Tocris/GW 803430/4242/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/GW 803430/4242/50/50 mg

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Tocris

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4242/50

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Description:MCH₁antagoNIST

ChemicalName:6-(4-Chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-thieno[3,2-d]pyrimidin-4(3H)-one

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivemelanin-concentratinghormonereceptor1(MCH₁)antagonist(IC₅₀=9.3nM).Displaysantiobesityandantidepressant-likeeffectsinratsandmice.Orallyactive.

LicensingInformation

SoldforresearchpurposesunderagreementfromGlaxoSmithKline.

TechnicalData

M.Wt	481.99
Formula	C₂₅H₂₄ClN₃O₃S
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	515141-51-2
PubChemID	9826520
InChIKey	MWULMTACIBZPGN-UHFFFAOYSA-N
Smiles	ClC(C=C3)=CC=C3C(S2)=CC1=C2C(N(C4=CC(OC)=C(OCCN5CCCC5)C=C4)C=N1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	1eq.HCl	14.75	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight481.99.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.07mL	10.37mL	20.75mL
5mM	0.41mL	2.07mL	4.15mL
10mM	0.21mL	1.04mL	2.07mL
50mM	0.04mL	0.21mL	0.41mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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TechnicalData

SolubilityData

PreparingStockSolutions

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