Tocris GPCR ligands Tocris信号通路抑制剂,Tocris/ICI 199,441 hydrochloride/0778/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/ICI 199,441 hydrochloride/0778/50/50 mg

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Tocris/ICI 199,441 hydrochloride/0778/50/50 mg

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Tocris

货号 /

0778/50

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4000-520-616

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Description:PotentκagoNIST

ChemicalName:2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Highlypotentκagonist,146-foldmoreactivethanU-50488(Cat.No.0495)invitro.

LicensingInformation

SoldwiththepermissionofAstraZenecaUKLtd.

CompoundLibraries

ICI199,441hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	427.8
Formula	C₂₁H₂₄Cl₂N₂O.HCl
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	115199-84-3
PubChemID	3082717
InChIKey	VFLWVWZSDBTGQJ-VEIFNGETSA-N
Smiles	ClC1=C(Cl)C=C(CC(N([C@@]([H])([C@]3=CC=CC=C3)CN2CCCC2)C)=O)C=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

Solubility	Solubleto100mMinDMSOandto50mMinethanol

Solubility

Solubleto100mMinDMSOandto50mMinethanol

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight427.8.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.34mL	11.69mL	23.38mL
5mM	0.47mL	2.34mL	4.68mL
10mM	0.23mL	1.17mL	2.34mL
50mM	0.05mL	0.23mL	0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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