BiologicalActivity
Sphingosine-1-phosphate(S1P)receptorantagonist,highlyselectiveforS1P2(EDG-5).InhibitsS1PbindingtohumanS1P2receptorswithanIC50valueof17.6nM.Atconcentrationsupto10μM,displays4.2%inhibitionofS1P3anddoesnotantagonizeS1P1.EnhancesS1P-inducedangiogenesisinvivo.
CompoundLibraries
JTE013isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 408.29 |
| Formula | C17H19N7OCl2 |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 547756-93-4 |
| PubChemID | 10223146 |
| InChIKey | RNSLRQNDXRSASX-UHFFFAOYSA-N |
| Smiles | CC(C)C1=C2C(C)=NN(C)C2=NC(NNC(=O)NC2=CC(Cl)=NC(Cl)=C2)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 40.83 | 100 | |
| ethanol | 40.83 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight408.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.45mL | 12.25mL | 24.49mL |
| 5mM | 0.49mL | 2.45mL | 4.9mL |
| 10mM | 0.24mL | 1.22mL | 2.45mL |
| 50mM | 0.05mL | 0.24mL | 0.49mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。