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Tocris/L-741,742 hydrochloride/1004/50/50 mg
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Tocris/L-741,742 hydrochloride/1004/50/50 mg
品牌 / 
Tocris
货号 / 
1004/50
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4000-520-616
Description:HighlyselectiveD4antagoNIST
ChemicalName:5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazolehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ApotentandhighlyselectiveD4dopaminereceptorantagonist,withKivaluesof>1700,770and3.5nMatclonedhumanD2,D3andD4receptors.

LicensingInformation

SoldwiththepermissionofMerckSharpandDohmeLtd.

TechnicalData

M.Wt417.38
FormulaC23H25N2ClO.HCl
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber874882-93-6
PubChemID133633
InChIKeyLLBLNMUONVVVPG-UHFFFAOYSA-N
SmilesCl.CC1=C(ON=C1C1CCN(CCC2=CC=CC=C2)CC1)C1=CC=C(Cl)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO4.1710

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight417.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.4mL11.98mL23.96mL
5mM0.48mL2.4mL4.79mL
10mM0.24mL1.2mL2.4mL
50mM0.05mL0.24mL0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet