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Description:HighlyselectiveD4antagoNIST
ChemicalName:5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazolehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
ApotentandhighlyselectiveD4dopaminereceptorantagonist,withKivaluesof>1700,770and3.5nMatclonedhumanD2,D3andD4receptors.
LicensingInformation
SoldwiththepermissionofMerckSharpandDohmeLtd.
TechnicalData
M.Wt | 417.38 |
Formula | C23H25N2ClO.HCl |
Storage | StoreatRT |
Purity | ≥98%(HPLC) |
CASNumber | 874882-93-6 |
PubChemID | 133633 |
InChIKey | LLBLNMUONVVVPG-UHFFFAOYSA-N |
Smiles | Cl.CC1=C(ON=C1C1CCN(CCC2=CC=CC=C2)CC1)C1=CC=C(Cl)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 4.17 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight417.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.4mL | 11.98mL | 23.96mL |
5mM | 0.48mL | 2.4mL | 4.79mL |
10mM | 0.24mL | 1.2mL | 2.4mL |
50mM | 0.05mL | 0.24mL | 0.48mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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