进口Tocris现货 Tocris GPCR ligands,Tocris/LG 101506/3508/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/LG 101506/3508/50/50 mg

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Tocris

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3508/50

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4000-520-616

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Description:SelectiveRXRmodulator

AlternativeNames:LG1506

ChemicalName:(2E,4E,6Z)-7-[2-(2,2-Difluoroethoxy)-3,5-bis(1,1-dimethylethyl)phenyl]-3-methyl-2,4,6-octatrienoicacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveRXRmodulator(K_ivaluesare3,9and11forRXRα,RXRβandRXRγrespectively).DisplayspoorbindingaffinityforRARisoforms(K_ivaluesare2746,3516and>10,000nMforRARα,RARβandRARγrespectively).BindingtoRXRresultsinselectiveactivationofRXR:PPARγ,RXR:PPARαandRXR:PPARδheterodimers.

TechnicalData

M.Wt	420.53
Formula	C₂₅H₃₄F₂O₃
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	331248-11-4
PubChemID	9845057
InChIKey	BHIBZAZKKARFIM-XRYBSMBUSA-N
Smiles	CC(C)(C)C1=CC(/C(C)=CC=CC(C)=CC(O)=O)=C(OCC(F)F)C(C(C)(C)C)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	42.05	100
	ethanol	21.03	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight420.53.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.38mL	11.89mL	23.78mL
5mM	0.48mL	2.38mL	4.76mL
10mM	0.24mL	1.19mL	2.38mL
50mM	0.05mL	0.24mL	0.48mL

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