BiologicalActivity
Partialagonistofhydroxycarboxylicacidreceptor2(HCA2)(Ki=0.55μM).Thoughttolowerplasmavery-low-densitylipoprotein(VLDL)-triglyceridelevelsbyaffectinghepaticVLDLproductioninnormolipidemicC57BL/6mice.
TechnicalData
| M.Wt | 168.19 |
| Formula | C8H12N2O2 |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 92933-48-7 |
| PubChemID | 6485181 |
| InChIKey | ZJTXSGLJNBAMJS-UHFFFAOYSA-N |
| Smiles | CCCCC1=CC(C(O)=O)=NN1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 16.82 | 100 | |
| ethanol | 16.82 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight168.19.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 5.95mL | 29.73mL | 59.46mL |
| 5mM | 1.19mL | 5.95mL | 11.89mL |
| 10mM | 0.59mL | 2.97mL | 5.95mL |
| 50mM | 0.12mL | 0.59mL | 1.19mL |
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