请使用支持JavaScript的浏览器! Tocris厂家直采,平行进口 Tocris Bioscience报价单,Tocris/Lyn peptide inhibitor/2265/1/1 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城
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Tocris/Lyn peptide inhibitor/2265/1/1 mg
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Tocris/Lyn peptide inhibitor/2265/1/1 mg
品牌 / 
Tocris
货号 / 
2265/1
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数    量:
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4000-520-616
Description:InhibitsLyn-dependentactivitiesofIL-5receptor;cell-permeable
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Cell-permeableinhibitorofLyn-dependenteffectsoftheIL-5receptor.BlocksbindingofLyntyrosinekinasetoβcsubunitofIL-3/GM-CSF/IL-5receptors,blockingLynactivation.InhibitsIL-5receptor-mediatedeosinophildifferentiationandsurvivalinvitro.Inhibitsairwayeosinophilicinflammationinmousemodelofasthma.

TechnicalData

M.Wt2370.91
FormulaC115H184N30O24
SequenceYGYRLRRKWEEKIPNP

(Modifications:Tyr-1=Octadecanoyl-Tyr,Pro-16=C-terminalamide)

StorageDesiccateat-20°C
CASNumber222018-18-0
PubChemID90001265
InChIKeyMITSVNFZLBORMW-QMGLJYLZSA-N
SmilesCCCCCCCCCCCCCCCCCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(N)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto10mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight2370.91.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.42mL2.11mL4.22mL
5mM0.08mL0.42mL0.84mL
10mM0.04mL0.21mL0.42mL
50mM0.01mL0.04mL0.08mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet