Tocris厂家直采，平行进口品牌试剂实验Tocris Bioscience代理,Tocris/MJ 15/4063/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/MJ 15/4063/50/50 mg

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Tocris

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4063/50

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4000-520-616

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Description:PotentandselectiveCB₁antagoNIST

ChemicalName:5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(3-pyridinylmethyl)-1H-pyrazole-3-carboxamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveCB₁receptorantagonist(K_i=27.2pM,IC₅₀=118.9pMforratCB₁receptors).Exhibitspotencyinobesityandhyperlipidemiamodels;inhibitsfoodintakeandincreasesinbodyweightindiet-inducedobeseratsandmice.

LicensingInformation

Soldunderlicence.

CompoundLibraries

MJ15isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	471.77
Formula	C₂₃H₁₇Cl₃N₄O
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	944154-76-1
PubChemID	59377482
InChIKey	PJEIKJFNEFJFLA-UHFFFAOYSA-N
Smiles	ClC1=CC(Cl)=CC=C1N2C(C3=CC=C(Cl)C=C3)=C(C)C(C(NCC4=CC=CN=C4)=O)=N2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	47.18	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight471.77.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.12mL	10.6mL	21.2mL
5mM	0.42mL	2.12mL	4.24mL
10mM	0.21mL	1.06mL	2.12mL
50mM	0.04mL	0.21mL	0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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