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Tocris/ML 145/4172/50/50 mg
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Tocris/ML 145/4172/50/50 mg
品牌 / 
Tocris
货号 / 
4172/50
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数    量:
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4000-520-616
Description:GPR35antagoNIST
ChemicalName:2-Hydroxy-4-[4-(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoylamino]benzoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveantagonistfortheGPR35orphanreceptorGPCR(IC50=20.1nM).Over1000-foldmoreselectiveforGPR35comparedtoGPR55antagonists.

TechnicalData

M.Wt482.57
FormulaC24H22N2O5S2
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber1164500-72-4
PubChemID2286812
InChIKeyCOFMYJWNXSFLKQ-QIROLCGISA-N
SmilesO=C(NC3=CC=C(C(O)=O)C(O)=C3)CCCN2C(/C(SC2=S)=C/C(C)=C/C1=CC=CC=C1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO48.26100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight482.57.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.07mL10.36mL20.72mL
5mM0.41mL2.07mL4.14mL
10mM0.21mL1.04mL2.07mL
50mM0.04mL0.21mL0.41mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet