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Tocris/ML 354/5387/50/50 mg

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Tocris

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5387/50

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4000-520-616

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Description:SelectivePAR₄antagoNIST

ChemicalName:1-Methyl-5-nitro-3-phenyl-1H-indole-2-methanol

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectivePAR₄antagonist(IC₅₀=140nM).Exhibits70-foldselectivityforPAR₄overPAR₁.

TechnicalData

M.Wt	282.29
Formula	C₁₆H₁₄N₂O₃
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	89159-60-4
PubChemID	752812
InChIKey	GNJUKVGDCUKDLF-UHFFFAOYSA-N
Smiles	CN2C1=CC=C([N+]([O-])=O)C=C1C(C3=CC=CC=C3)=C2CO

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	28.23	100
	ethanol	2.82	10mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight282.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.54mL	17.71mL	35.42mL
5mM	0.71mL	3.54mL	7.08mL
10mM	0.35mL	1.77mL	3.54mL
50mM	0.07mL	0.35mL	0.71mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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