Tocris产品目录价格 Tocris Bioscience美元价/进货价,Tocris/Methylprednisolone/4819/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/Methylprednisolone/4819/50/50 mg

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Tocris

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4819/50

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4000-520-616

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Description:GlucocorticoidreceptoragoNIST

ChemicalName:11β,17β,21-Trihydroxy-6α-methyl-1,4-pregnADIene-3,20-dione

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Glucocorticoidreceptor(GR)agonist.Displaysanti-inflammatoryandantioxidantproperties.Attenuatesapoptosisinoligodendrocytesafterinjurystimuli.UpregulatesexpressionofBcl-x_LviadirectbindingoftheGR/STAT5complex.Neuroprotective.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

CompoundLibraries

MethylprednisoloneisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	374.47
Formula	C₂₂H₃₀O₅
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	83-43-2
PubChemID	6741
InChIKey	VHRSUDSXCMQTMA-PJHHCJLFSA-N
Smiles	O=C1C=C[C@@]2(C)C([C@@H](C)C[C@]3([H])[C@@]([H])2[C@@H](O)C[C@@]4(C)[C@]([H])3CC[C@](C(CO)=O)4O)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	37.45	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight374.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.67mL	13.35mL	26.7mL
5mM	0.53mL	2.67mL	5.34mL
10mM	0.27mL	1.34mL	2.67mL
50mM	0.05mL	0.27mL	0.53mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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