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Description:Selectiveβ1antagoNIST
ChemicalName:1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanolhemitartrate
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Selectiveβ1-adrenoceptorantagonist(Kivaluesare47,2960and10100nMforβ1,β2andβ3adrenoceptorsrespectively).Inhibitsspontaneousendothelin-1productioninvitroanddisplaysantihypertensiveandantianginalactivityinvivo.
CompoundLibraries
MetoprololtartrateisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 342.4 |
Formula | C15H25NO3.½C4H6O6 |
Storage | DesiccateatRT |
Purity | ≥99%(HPLC) |
CASNumber | 56392-17-7 |
PubChemID | 6420057 |
InChIKey | YGULWPYYGQCFMP-UHFFFAOYSA-N |
Smiles | O=C(O)C(O)C(O)C(O)=O.OC(CNC(C)C)COC1=CC=C(CCOC)C=C1.OC(CNC(C)C)COC2=CC=C(CCOC)C=C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 34.24 | 100 | |
water | 34.24 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight342.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.92mL | 14.6mL | 29.21mL |
5mM | 0.58mL | 2.92mL | 5.84mL |
10mM | 0.29mL | 1.46mL | 2.92mL |
50mM | 0.06mL | 0.29mL | 0.58mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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