进口Tocris品牌清关代理美国Tocris Bioscience公司,Tocris/Mifepristone/1479/100/100 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/Mifepristone/1479/100/100 mg

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Tocris

货号 /

1479/100

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4000-520-616

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Description:ProgesteroneandglucocorticoidreceptorantagoNIST

AlternativeNames:RU486,RU38486

ChemicalName:(11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propynyl)-estra-4,9-dien-3-one

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveantagonistatprogesterone(PR)andglucocorticoid(GR)receptorsinvitroandinvivo.IsasilentantagonistatPRandhasahigheraffinitythanprogesterone.HashigheraffinityforGRthandexamethasone(Cat.No.1126).

CompoundLibraries

MifepristoneisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	429.6
Formula	C₂₉H₃₅NO₂
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	84371-65-3
PubChemID	55245
InChIKey	VKHAHZOOUSRJNA-GCNJZUOMSA-N
Smiles	[H][C@@]23CCC1=CC(CCC1=C2[C@@H]([C@]5=CC=C(N(C)C)C=C5)C[C@@]4(C)[C@]([H])3CC[C@@](C#CC)4O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	42.96	100
	ethanol	21.48	50mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight429.6.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.33mL	11.64mL	23.28mL
5mM	0.47mL	2.33mL	4.66mL
10mM	0.23mL	1.16mL	2.33mL
50mM	0.05mL	0.23mL	0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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SolubilityData

PreparingStockSolutions

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