BiologicalActivity
Selectiveantagonistatprogesterone(PR)andglucocorticoid(GR)receptorsinvitroandinvivo.IsasilentantagonistatPRandhasahigheraffinitythanprogesterone.HashigheraffinityforGRthandexamethasone(Cat.No.1126).
CompoundLibraries
MifepristoneisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 429.6 |
| Formula | C29H35NO2 |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 84371-65-3 |
| PubChemID | 55245 |
| InChIKey | VKHAHZOOUSRJNA-GCNJZUOMSA-N |
| Smiles | [H][C@@]23CCC1=CC(CCC1=C2[C@@H]([C@]5=CC=C(N(C)C)C=C5)C[C@@]4(C)[C@]([H])3CC[C@@](C#CC)4O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 42.96 | 100 | |
| ethanol | 21.48 | 50mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight429.6.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.33mL | 11.64mL | 23.28mL |
| 5mM | 0.47mL | 2.33mL | 4.66mL |
| 10mM | 0.23mL | 1.16mL | 2.33mL |
| 50mM | 0.05mL | 0.23mL | 0.47mL |
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