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Description:Syntheticcorticosteroid;anti-inflammatoryagent
ChemicalName:11β,16α)-9,21-Dichloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl2-furoate
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potentsyntheticcorticosteroid;displaysagoNISTactivityatglucocorticoidandprogesteronereceptors.Exhibitsanti-inflammatoryeffects.
TechnicalData
| M.Wt | 521.43 |
| Formula | C27H30Cl2O6 |
| Storage | Storeat-20°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 83919-23-7 |
| PubChemID | 441336 |
| InChIKey | WOFMFGQZHJDGCX-ZULDAHANSA-N |
| Smiles | O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@@](Cl)2[C@@H](O)C[C@@]4(C)[C@]([H])3C[C@@H](C)[C@@](OC(C5=CC=CO5)=O)4[C@@](CCl)=O)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 52.14 | 100 | |
| ethanol | 5.21 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight521.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.92mL | 9.59mL | 19.18mL |
| 5mM | 0.38mL | 1.92mL | 3.84mL |
| 10mM | 0.19mL | 0.96mL | 1.92mL |
| 50mM | 0.04mL | 0.19mL | 0.38mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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